Genetics & Genetic Disorders

Dr Sergey V. Suchkov, MD, PhD Sergey Suchkov was born in the City of Astrakhan, Russia, in a family of dynasty medical doctors. In 1980, graduated from Astrakhan State Medical University and was awarded with MD. In 1985, Suchkov maintained his PhD as a PhD student of the I.M. Sechenov Moscow Medical Academy and Institute of Medical Enzymology. In 2001, Suchkov maintained his Doctor Degree at the National Institute of Immunology, Russia. From 1989 through 1995, Dr Suchkov was being a Head of the Lab of Clinical Immunology, Helmholtz Eye Research Institute in Moscow. From 1995 through 2004 - a Chair of the Dept for Clinical Immunology, Moscow Clinical Research Institute (MONIKI). In 1993-1996, Dr Suchkov was a Secretary-in-Chief of the Editorial Board, Biomedical Science, an international journal published jointly by the USSR Academy of Sciences and the Royal Society of Chemistry, UK. At present, Dr Sergey Suchkov, MD, PhD, is: ● Professor, Director, Center for Personalized Medicine, I.M.Sechenov First Moscow State Medical University and Dept of Clinical Immunology, A.I.Evdokimov Moscow State Medical and Dental University; ● Professor, Chair, Dept for Translational Medicine, Moscow Engineering Physical Institute (MEPhI), Russia ● Secretary General, United Cultural Convention (UCC), Cambridge, UK. Dr Suchkov is a member of the: ● New York Academy of Sciences, USA ● American Chemical Society (ACS), USA; ● American Heart Association (AHA), USA; ● European Association for Medical Education (AMEE), Dundee, UK; ● EPMA (European Association for Predictive, Preventive and Personalized Medicine), Brussels, EU; ● ARVO (American Association for Research in Vision and Ophthalmology); ● ISER (International Society for Eye Research); ● Personalized Medicine Coalition (PMC), Washington, DC, USA ● All-Union (from 1992 - Russian) Biochemical Society; ● All-Union (from 1992 - Russian) Immunological Society. Dr Suchkov is a member of the Editorial Boards of “Open Journal of Immunology”, EPMA J., American J. of Cardiovascular Research and “Personalized Medicine Universe”

Translational Medicine

Magnus S. Magnusson, Research Professor, founder and director of the Human Behavior Laboratory, University of Iceland. PhD in 1983, University of Copenhagen. Author of the T-pattern model and detection software THEMETM (PatternVision.com), focused on real-time organization of behavior. Co-directed DNA analysis. Numerous papers and talks/keynotes in ethology, neuroscience, mathematics, religion, proteomics, mass spectrometry and nanoscience. Deputy Director 1983-1988, in Museum of Mankind, National Museum of Natural History, Paris. Repeatedly invited temporary Professor at the University of Paris, V, VIII and XIII. In collaboration between now nearly 40 universities initiated 1995 at University of Paris V, Sorbonne, based on “Magnusson’s analytical model”.

Genetic Disorders

Simon Berkovich has completed his PhD at the age of 27 years from the USSR Academy of Sciences. He played a leading role in a number of advanced research and development projects. He has several hundred prestigious professional publications in various areas of physics, electronics, computer science, and biological cybernetics. He is an author of six books and holds 30 patents. In 2002, he was elected a member of the European Academy of Sciences "for an outstanding contribution to computer science and the development of fundamental computational algorithms". In 2014, he won the GWU Technology Transfer Innovation Competition, patent is considered.

Genome Functionality, Information content of DNA, Organism’s development, Principle of requisite variety

Dr Gupta has passion for writing. He has published 250 papers and 22 books and many Popular Science articles many of which were translated in Indian and foreign languages. He has written news articles for papers such as Hindu, Deccan Chronicle, and many regional newspapers in Indian languages. He had his own column in English news paper Indian Express. In addition to newspapers he has also published articles in Magazines published by Delhi Press and many other regional magazines .Dr Gupta’s books and popular science articles were translated in many Indian and Japanese languages. He has published books besides from India (Delhi, Bangalore, Jaipur, Rajkot, Pune and Bikaner), USA, Japan and Germany.

Nanotechnology has opened up, in addition to inheritance, many other diversified avenues of applications for the fundamental building block of genetic makeup of all living beings. DNA has become ‘hot molecule’ in biology (including agriculture and medicine), chemistry, and physics (including computer science). Nanopore technology has made a big dent in management of genetic disorders by way of sequencing of DNA made easy. The mitochondrial replacement therapy in cases where mitochondrial DNA mutated and stopped supplying energy to the living cell(s), is a step forward towards revitalising dying vital human organs. Because of its properties, self-assembling, self-replicating, storage of memory, and adopting various states and conformations, DNA is the best material for the designing of electric circuits and DNA-based computing and nanorobotics. At present, many research groups are exploiting ‘programmable self-assembly’ properties of nucleic acids in creating rationally designed nanoshapes and nanomachines for many different uses. DNA origami and the related techniques are particularly emphasized in the evolution of structural DNA Nanotechnology, dealing with high-quality shapes, and the software that enable user-friendly design and fabrication of DNA nanoobjects. Newly synthesized DNA-based dendrimer, the Nanocages, are highly interesting molecular constructs; the cavities of these nanometer-sized objects can be employed as carriers of smaller molecules, which is of critical importance in medicine for drug or gene delivery in living organisms. Both DNA biomarkers and DNA tumor markers are discrete in nature, however, share the property of being quantitative with positive measurement values of their type, and therefore serve as a very specific and sensitive diagnostic tool. DNA biomarkers are generally measured in the blood, and tumor DNA biomarkers are measured in tumor tissue.

Jan Lukas Robertus was appointed as a Consultant Cardiothoracic Pathologist at The Royal Brompton and Harefield NHS Foundation Trust in February 2015. He has previously worked as a Consultant Cardiothoracic Pathologist at the Erasmus Medical Centre, Rotterdam, the Netherlands. He is the lead pathologist for computational pathology. He is also co-lead for the Royal Brompton Cardiac Morphology UnJan Lukas Robertus, received his MD at the University of Utrecht and completed his PhD and registrar program in Pathology at the University of Groningen, the Netherlands. Heit and is member of the Brompton Cardiac Morphology Steering Committee. He is Honorary Senior Clinical Lecturer at the National Heart and Lung Institute, Imperial College London. His main research interests are computational pathology, specifically in the areas of thoracic oncology, cardiomyopathies, aortopathies, cardiac and pulmonary transplantation.

computational pathology

Ali Alavi has a B.A.Sc. in Clinical Laboratory Science from College of Health and Caring, Umea, Karolinska Institution, Sweden. He has 21 years’ experience in various laboratories and is currently the Supervisor of Premarital Genetic Screening Program in Diagnostic Genomic Division in Hamad Medical Corporation, Qatar.

Genetic Screening